CBD For Inflammation
The Best CBD for Inflammation Relief
Inflammation is our body's first line of defense against irritation, injury, or infection.
Are you aware that sometimes what should have been our bodies' natural defenses can actually worsen our health problems?
Body Effects of Inflammation
As mentioned above, inflammation can worsen diseases and disorders.
For instance, rheumatoid arthritis causes systemic inflammation and affects multiple joints and organs.
Increasing the number of immune cells caused by cytokines only worsens inflammation.
Chronic inflammation of the joints can result in permanent joint damage and deformities.
Chron's disease is distinguished by the increased immune cell recruitment brought on by cytokines, which results in the development of ulcers, thickening of the intestinal wall, and the formation of adhesions.
Both bowel obstructions and issues with absorption are brought on by these.
Multiple sclerosis gets worse because of an unfavorable immune reaction to the myelin sheath of the axon.
Transmission of signals is hampered as a result of the cytokines attacking the myelin sheath of the neuron's axon, leading to crippling motor and sensory issues.
Epilepsy can be influenced by inflammation.
In addition to making the neurons more excitable, which could cause a seizure, the presence of cytokines also makes excitotoxicity worse, which accelerates the death of neurons.
Excitatory neurotransmitters, such as glutamate, can overexcite neurons to the point where they begin to die. This condition is known as excitotoxicity.
Despite what you may think, immune cells have an impact on cancer because cancer cells have the ability to "hijack" a certain type of immune cell.
These immune cells protect cancer cells from destruction and even act as chaperones for them, allowing them to metastasize.
Because of the effect of inflammation on excitatory neurotransmitters and excitotoxicity, it can exacerbate anxiety, depressive disorders, and autism.
So, inflammation can be so unpleasant at times that it can actually harm us rather than help us.
Medications are administered to alleviate symptoms, reduce inflammation, and, in some cases, prevent the immune system from attacking the body.
Unfortunately, while these drugs do help, they also have side effects that can be harmful to the body.
Pain occurs where there is inflammation.
A sad truth, but a truth nonetheless.
And, you know, we can all blame it on cytokines (again!).
Because cytokines stimulate neuronal pain receptors, the longer they remain in the system, the longer they activate our pain receptors.
In fact, cytokines play an important role in pathologic pain, which is pain caused by an injury.
They can aggravate pain from simple muscle injuries such as strains, cramps, and spasms, and they can also aggravate neuropathic pain caused by multiple sclerosis, diabetes, cancer, and sciatica.
CBD Is a Superb Anti-Inflammatory Substance
Even though THC is a strong anti-inflammatory substance, CBD really steals the show.
Why?
When it comes to controlling inflammation, CBD is just as effective as THC, but it won't get you high.
It is also a powerful antioxidant that can help protect cells from excitotoxicity!
Let's look at how CBD works to reduce inflammation.
Neuroinflammation and CBD
Let me tell you, CBD gets even more interesting.
It specifically targets mitochondrial dysfunction in cells.
The mitochondria, also known as the cell's powerhouse, are responsible for energy production and release.
However, their metabolism generates reactive oxygen species.
When stressed or injured, the mitochondria produce more ROS, release more intracellular calcium, and exacerbate inflammation.
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How Does CBD Help Pain?
Researchers believe CBD can help reduce pain because it is a powerful anti-inflammatory compound that can inhibit cytokine production.
According to the theory, both acute and chronic pain should be relieved.
But wait, there's more!
However, CBD does not end there in terms of pain relief because it stimulates another receptor to produce analgesic effects.
Do you recall the vanilloid receptor? For good reason, it's also known as the capsaicin receptor!
Capsaicin causes skin irritation. When you first apply it to your skin, you will experience a painful, burning sensation. You'll feel blessed with relief after a while.
Why?
The pain you feel is reduced because capsaicin desensitizes the sensory neurons.
CBD can now stimulate the vanilloid receptors of sensory neurons, leading to their desensitization.
CBD is a potent analgesic that can help people suffering from chronic and neuropathic pain.
Of course, there's more.
Pain regulation is one of the effects of our endocannabinoids when they bind to the CB1 and CB2 receptors, but because they are easily degraded, their effects are fleeting.
Fortunately, CBD can address the rapid degradation of endocannabinoids by allowing them to remain in the system for longer periods of time.
Would you like more?
CBD's stimulation of serotonin receptors is also thought to produce analgesia.
So, what kinds of pain can CBD alleviate?
While the research is still in its early stages, CBD has been shown to help with a variety of pain conditions, from migraines to arthritis and even neuropathic pain.
Is CBD the ideal analgesic and anti-inflammatory compound?
Through various means, CBD is thought to reduce inflammation and pain, and it has an excellent safety profile with few side effects.
It is also a strong antioxidant that can aid in preventing the formation of free radicals, is well-tolerated, and non-intoxicating.
Our current knowledge provides strong evidence that CBD is an efficient and safe anti-inflammatory agent, even though future research and data will likely reveal even more fascinating insights about its effects.
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